For patients at high risk of Alzheimer’s disease, taking a combination of vitamins E and C plus ibuprofen significantly reduces their risk, results of a longitudinal study suggest.
Specifically, the combination seems to benefit people who carry a variant of the gene for apolipoprotein, APOE-4, which is known to put them at high risk for developing Alzheimer’s disease.
“We found that for people at low risk, taking vitamin C and E alone is sufficient to further reduce their risk,” Dr. Majid Fotuhi told Reuters Health. “But for those with (APOE-4), the combination exerts a synergistic benefit.”
Fotuhi, from Johns Hopkins University in Baltimore, and his associates followed nearly 5000 elderly residents of Cache County in Utah for 8 years, taking into account their regular consumption of vitamins C and E, and ibuprofen.
